| Product Name | Apolipoprotein A1 antibody [1409] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [1409] to Apolipoprotein A1Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids; an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. |
| Immunogen | Full length native protein (purified) (Human plasma). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 1409 |
| Host Species | Mouse |
| Tested Applications | EIARIA |
| EIA: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | MGC117399 |
|---|---|
| Target | Apolipoprotein A1 |
| Tissue Specificity | does not cross-react with APO A II or Apo B. |
| Cellular Localization | Secreted |
| Application Notes | EIA: Use at an assay dependent dilution. RIA: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | 0.015M Potassium phosphate buffer, 0.15M sodium chloride, pH 7.2, containing 0.1% sodium azide |
