Rabbit Polyclonal antibody to Apolipoprotein CIIThis gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Apolipoprotein C2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Species Reactivity
HumanMouseMonkeyRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
apolipoprotein C-II , APOC II , APO CII , APOC2
Target
Apolipoprotein CII
Tissue Specificity
Recognizes endogenous levels of Apolipoprotein C2 protein.
Application
Application
Western blot analysis of Apolipoprotein C2 expression in HeLa (A); mouse liver (B); rat liver (C) whole cell lysates.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.