Application
Immunohistochemistry of APO-E in human liver tissue with APO-E antibody at 2.5 μg/ml.Application
Western blot analysis of APO-E in human brain tissue lysate with APO-E antibody at (A) 0.5 and (B) 1 μg/mL.| Product Name | Apolipoprotein E antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Apolipoprotein EChylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008] |
| Immunogen | APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIHC-PWB |
| WB: 1 - 2 ug/ml | |
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | APOE , APO-E , LDLCQ5 , AD2 , apolipoprotein E , LPG |
|---|---|
| Target | Apolipoprotein E |
Application
Immunohistochemistry of APO-E in human liver tissue with APO-E antibody at 2.5 μg/ml.
Application
Western blot analysis of APO-E in human brain tissue lysate with APO-E antibody at (A) 0.5 and (B) 1 μg/mL.| Application Notes | WB: 1 - 2 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stored At 4ºc For Three Months And -20ºc, Stable For Up To One Year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
