Application
Sample (30 ug of whole cell lysate) A: Jurkat 7.5% SDS PAGE diluted at 1:1000Application
Immunofluorescence analysis of methanol-fixed HeLa, using APPBP2 antibody at 1:100 dilution.Application
Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using APPBP2 antibody at 1:100 dilution.| Product Name | APPBP2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to APPBP2 (amyloid beta precursor protein (cytoplasmic tail) binding protein 2)The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human APPBP2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Zebrafish, Xenopus laevis, Chicken, Rhesus MonkeyMouse (100%), Rat (99%), Zebrafish (96%), Xenopus laevis (88%), Chicken (98%), Rhesus Monkey (100%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | HS.84084 antibody, KIAA0228 antibody, PAT1 antibody, APPBP2 antibody, APP-BP2 antibody, protein interacting with APP tail 1 antibody, amyloid protein-binding protein 2 antibody, amyloid beta precursor protein-binding protein 2 antibody, amyloid beta precur |
|---|---|
| Molecular Weight(MW) | 67 kDa (note) (3) |
| Cellular Localization | Nucleus , Cytoplasm , cytoskeleton , Membrane; Peripheral membrane protein , Nucleus , Cytoplasm , cytoskeleton , Membrane |
Application
Sample (30 ug of whole cell lysate) A: Jurkat 7.5% SDS PAGE diluted at 1:1000
Application
Immunofluorescence analysis of methanol-fixed HeLa, using APPBP2 antibody at 1:100 dilution.
Application
Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using APPBP2 antibody at 1:100 dilution.| Positive Control | Jurkat , Raji |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
