Rabbit polyclonal to APRILAPRIL (a proliferation-inducing ligand) is a newly identified member of the tumor necrosis factor (TNF) family. Ectopic expression of APRIL is associated with the upregulation of X-linked inhibitor of apoptosis protein (XIAP) and may act as antiapoptotic factor. Although transcripts of APRIL are of low abundance in normal tissues, high levels of mRNA are detected in transformed cell lines, and in human cancers of colon, thyroid, and lymphoid tissues in vivo.
Immunogen
Synthetic peptide corresponding to amino acids 1-17 of APRIL.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
For WB: Use at a concentration of 2 μg/ml. Detects a band of approximately 30 kDa. Optimal dilutions/concentrations should be determined by the researcher.
Western blot analysis of APRIL in HL-60 whole cell lysate using APRIL antibody at 2 ug/ml.
Positive Control
HL-60 whole cell lysate
Application Notes
For WB: Use at a concentration of 2 μg/ml. Detects a band of approximately 30 kDa. Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.