Rabbit Polyclonal antibody to APRILThe protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010]
Immunogen
APRIL antibody was raised against a synthetic peptide corresponding to amino acids within a extracellular domain of human APRIL.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
IHC: 10 ug/mL
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Immunohistochemistry of APRIL in human prostate tissue with APRIL antibody at 10 ug/mL.
Application
Western blot analysis of APRIL expression in Jurkat cells with APRIL antibody at 1 ug/mL (A), 2 ug/mL (B), and 4 ug/mL (C).
Application Notes
IHC: 10 ug/mL
Additional Information
Form
Liquid
Storage Instructions
Be stored at 4oC for three months and -20oC, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.