Application
Western blot of rat kidney lysate showing phospho-specific immunolabeling of the ~29k and 37k glycosylated form of the AQP2 protein phosphorylated at Ser 261 using Aquaporin 2 (phospho Ser261) antibody .| Product Name | Aquaporin 2 (phospho Ser261) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Aquaporin 2 (phospho Ser261)Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser261 conjugated to KLH |
| Modification | p-Ser261 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| Optimal working dilutions should be determined experimentally by the end user. | |
| Species Reactivity | Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | AQP-CD, AQP2, Aquaporin-CD, ADH water channel, Water channel protein for renal collecting duct, Collecting duct water channel protein, WCH-CD, aquaporin 2, aquaporin2, AQPCD, AquaporinCD, WCHCD, AQP CD, WCH CD, Aquaporin CD, Aquaporin 2 (phospho S261), Aqu |
|---|---|
| Target | Aquaporin 2 (phospho Ser261) |
| Molecular Weight(MW) | 29/37 (note) |
| Cellular Localization | Shuttles from vesicles to the apical membrane. |
Application
Western blot of rat kidney lysate showing phospho-specific immunolabeling of the ~29k and 37k glycosylated form of the AQP2 protein phosphorylated at Ser 261 using Aquaporin 2 (phospho Ser261) antibody .| Application Notes | Optimal working dilutions should be determined experimentally by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol. |
