Rabbit polyclonal antibody to Aquaporin 2Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Immunogen
The antiserum was produced against synthesized peptide derived from human Aquaporin 2.
Key Feature
Clonality
Polyclonal
Isotype
Cocktail
Host Species
Rabbit
Tested Applications
ELISAICC/IF
ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
AQP-CD, Aquaporin-CD, ADH water channel, Water channel protein for renal collecting duct, Aquaporin 2, Collecting duct water channel protein, WCH-CD, Aquaporin2, AQPCD, AquaporinCD, WCHCD, AQP CD, WCH CD, Aquaporin CD
Target
Aquaporin 2
Molecular Weight(MW)
28 kDa (note)
Tissue Specificity
Aquaporin 2 (Ab-256) Antibody detects endogenous levels of total Aquaporin 2 protein.
Cellular Localization
Shuttles from vesicles to the apical membrane.
Application
Application
Immunofluorescence analysis of HeLa cells, using Aquaporin 2 Antibody. The picture on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.