Rabbit polyclonal antibody to Argonaute protein 1Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).
Immunogen
Synthetic peptide
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFIHCWB
1:500 for WB
Species Reactivity
C.elegans
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
GERP95, Q99, AGO1, EIF2C1, EIF2C
Target
Argonaute protein 1
Application Notes
1:500 for WB
Additional Information
Form
Liquid
Storage Instructions
Product should be aliquoted and stored at -20∞C. Avoid repeated freeze/thaw cycles.