Rabbit Polyclonal antibody to ARH (low density lipoprotein receptor adaptor protein 1)The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human ARH. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (83%), Rat (83%), Bovine (85%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
ARH antibody, ARH1 antibody, ARH2 antibody, DKFZp586D0624 antibody, FHCB1 antibody, FHCB2 antibody, MGC34705 antibody, LDLRAP1 antibody, low density lipoprotein receptor adapter protein 1 antibody, autosomal recessive hypercholesterolemia protein antibody,
Molecular Weight(MW)
34 kDa (note) (2)
Cellular Localization
Cytoplasm
Application
Application
Sample (30 ug of whole cell lysate) A: U87-MG 12% SDS PAGE diluted at 1:1000
Application
Immunohistochemical analysis of paraffin-embedded human breast cancer, using ARH antibody at 1:500 dilution.
Positive Control
U87-MG
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.