Application
Western blot analysis of extracts from RAW264.7 cells, using ARHGEF12 Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | ARHGEF12 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to ARHGEF12May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ARHGEF12. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: 1:20000 Optimal dilutions should be determined experimentally by the end user. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Leukemiaassociated RhoGEF, ARHGEF12, Rho guanine nucleotide exchange factor 12, Leukemia-associated RhoGEF, Rho guanine nucleotide exchange factor12, Leukemia associated RhoGEF |
|---|---|
| Target | ARHGEF12 |
| Molecular Weight(MW) | 173 kDa (note) |
| Tissue Specificity | ARHGEF12 Antibody detects endogenous levels of total ARHGEF12 protein. |
| Cellular Localization | Translocated to the membrane upon stimulation. |
Application
Western blot analysis of extracts from RAW264.7 cells, using ARHGEF12 Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | ELISA: 1:20000 Optimal dilutions should be determined experimentally by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
