Application
WB ImageWestern blot analysis of human placenta extract probed with Mouse anti-Human Cytochrome P450 Aromatase followed by F(ab')2 Rabbit anti-Mouse IgG:HRP| Product Name | Aromatase antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [H4] to AromataseThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq, Jul 2008] |
| Immunogen | Synthetic peptide corresponding to amino acids 376 - 390 of human Aromatase. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2a |
| Clone Number | H4 |
| Host Species | Mouse |
| Tested Applications | ICC/IFIHC-PWB |
| Western Blotting: Max Dilution 1/250 Optimal dilution / concentration should be determined by the end user.: |
|
| Species Reactivity | HumanMouseChickenPigRatBaboonGoatHorseRabbitSheepBovineMarmosetBat |
| Concentration | 1mg/ml |
| Gene Synonyms | CYP19A1 CYPXIX P-450AROM ARO ARO1 CYP19 cytochrome P450 family 19 subfamily A polypeptide 1 CYAR CPV1 |
|---|---|
| Target | Aromatase |
| Tissue Specificity | This antibody recognizes a conserved epitope within cytochrome P450 Aromatase. |
Application
WB ImageWestern blot analysis of human placenta extract probed with Mouse anti-Human Cytochrome P450 Aromatase followed by F(ab')2 Rabbit anti-Mouse IgG:HRP| Application Notes | Western Blotting: Max Dilution 1/250 Optimal dilution / concentration should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | 0.1%Sodium Azide |
