| Product Name | ARTS antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to ARTSApoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF beta and, to a lesser extent, by other apoptotic agents, such as TNF alpha and Fas ligand. |
| Immunogen | Synthetic peptide: KNIQDNRVHCCLYFISPFGHG conjugated to KLH, corresponding to amino acids 247-266 of Human ARTS (with added N-terminal K). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a dilution of 1/15000. Detects a band of approximately 32 kDa. Optimal dilutions/concentrations should be determined by the end user. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Unpurified |
| Gene Synonyms | hCDCREL2, 603696, H5, hCDCREL-2, hucep-7, 5414, ARTS, O43236, hucep7, SEPT4, PNUTL2, CE5B3, hucep 7, hCDCREL 2 |
|---|---|
| Target | ARTS |
| Cellular Localization | Mitochondrial and Nuclear |
| Application Notes | WB: Use at a dilution of 1/15000. Detects a band of approximately 32 kDa. Optimal dilutions/concentrations should be determined by the end user. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Preservative: 15mM Sodium Azide; Constituents: 0.01M PBS. pH 7.4 |
