Application
Western blot analysis of Asb-3 in 15 ugs of human spleen cell lysate using at 1:1000 dilution.| Product Name | ASB3 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to ASB3The ankyrin repeat and SOCS box containing (Asb) protein family is comprised of members which each contain SOCS boxes but differ from other families of protein in the motifs they contain upstream of the SOCS box. SOCS boxes are carboxy terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. The gene is induced by all trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known. |
| Immunogen | Synthetic peptide: DSSENYIKMK corresponding to amino acids 66 to 75 of Human ASB3 and IRKGANKECQDDFGI corresponding to amino acids 166 to 180 of Human ASB3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a dilution of 1/500 - 1/1000. Predicted molecular weight: 62 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Synonyms | MGC996 605760 Q9Y575 FLJ10123 51130 ASB3 ASB-3 FLJ10421 MGC132002 MGC12531 ASB 3 |
|---|---|
| Target | ASB3 |
| Cellular Localization | Cytoplasmic |
Application
Western blot analysis of Asb-3 in 15 ugs of human spleen cell lysate using at 1:1000 dilution.| Application Notes | WB: Use at a dilution of 1/500 - 1/1000. Predicted molecular weight: 62 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium Azide; Constituents: PBS, 0.01mg/ml BSA |
