Rabbit Polyclonal antibody to ASBTThis gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). [provided by RefSeq, Mar 2010]
Immunogen
The immunogen is within the range 178-195a.a (Human).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-P
IHC-P(1:100-500):
Species Reactivity
Human
Predicted Reactivity
Horse, Dog
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
NTCP2 IBAT solute carrier family 10 (sodium/bile acid cotransporter family) member 2 PBAM SLC10A2 ISBT
Target
ASBT
Tissue Specificity
ASBT/SLC10A2
Application
Application
IHC-P analysis of mouse intestine using ASBT antibody at a dilution of 1:200.
Application Notes
IHC-P(1:100-500):
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and less than 0.09% sodium azide.