Application
ASXL1 antibody detects ASXL1 protein at nucleus in human esophagus carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human esophagus carcinoma. ASXL1 antibody diluted at 1:500.Application
ASXL1 antibody detects ASXL1 protein by western blot analysis. A. 50 µg 293T whole cell lysate/extract B. 50 µg whole cell lysate/extract of GFP-human ASXL1-transfected 293T cells ASXL1 antibody dilution: 1:5000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Product Name | ASXL1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to ASXL1 (additional sex combs like 1 (Drosophila))This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human ASXL1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | MouseMouse (93%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | KIAA0978 antibody MGC117280 antibody MGC71111 antibody ASXL1 antibody putative Polycomb group protein ASXL1 antibody additional sex combs-like protein 1 antibody additional sex combs like 1 (Drosophila) antibody |
|---|---|
| Molecular Weight(MW) | 165 kDa (note) |
| Tissue Specificity | Knockdown/Knockout validation was supported by references (PMID:26385183) |
| Cellular Localization | Nucleus |
Application
ASXL1 antibody detects ASXL1 protein at nucleus in human esophagus carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human esophagus carcinoma. ASXL1 antibody diluted at 1:500.
Application
ASXL1 antibody detects ASXL1 protein by western blot analysis. A. 50 µg 293T whole cell lysate/extract B. 50 µg whole cell lysate/extract of GFP-human ASXL1-transfected 293T cells ASXL1 antibody dilution: 1:5000 The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.| Positive Control | human ASXL1-transfected 293T cells |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
