Application
Western blot of ataxin 7 in transfected COS-1 cell lysate using| Product Name | Ataxin 7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Ataxin 7Spinocerebellar ataxia type 7 (SCA7) belongs to a class of hereditary neurodegenrative diseases characterized by abnormally expanded polyglutamine (CAG) repeats at the N-terminus. This autosomal dominant cerebellar ataxia primarily affects the cerebellum, retina, and brain stem and causes dementia, macular degeneration and other neurodegenerative characteristics. SCA7 gene encodes the ubiquitous 892 residue protein ataxin-7. This protein is typically located in the cytoplasm and on the nuclear membrane of normal brain neurons. In cells where there is a mutation of the SCA7 gene, ataxin 7 accumulates in intranuclear inclusions and can result in cell death. |
| Immunogen | Synthetic Peptide: M(1) S E R A A D D V R G E P R R A A(17) C |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCIHC-FIPWB |
| ICC/IF: 1:500: |
|
| Species Reactivity | HumanMouseDrosophilaRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | OPCA3 O15265 Ataxin 7 6314 164500 ATXN7 SCA7 ADCAII Ataxin7 |
|---|---|
| Target | Ataxin 7 |
Application
Western blot of ataxin 7 in transfected COS-1 cell lysate using| Application Notes | ICC/IF: 1:500: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 1 mg/ml BSA and 0.05% sodium azide. |
