Rabbit polyclonal to ATF2This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Immunogen
Synthetic peptide: GCGQRFTNEDHLAVH, corresponding to amino acids 13-27 of Human ATF2.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: Use at a concentration of 1 - 2 μg/ml. Detects a band of approximately 60 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouseRatXenopus
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
CREB2 HB16 TREB7 CRE-BP1
Target
ATF2
Cellular Localization
Nuclear
Application
Application
Detection of ATF2 in 293 cell lysate using ATF2 antibody at 2 ug/ml.
Positive Control
293 whole cell extract
Application Notes
WB: Use at a concentration of 1 - 2 μg/ml. Detects a band of approximately 60 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.