Rabbit Polyclonal antibody to AXL (phospho Tyr697)The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human AXL (pY697). The exact sequence is proprietary.
Modification
p-Tyr697
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
ARK AXL receptor tyrosine kinase Tyro7 AXL JTK11 UFO
Target
AXL (phospho Tyr697)
Tissue Specificity
Recognizes endogenous levels of AXL (pY697) protein.
Application
Application
Western blot analysis of AXL (pY697) expression in HEK293T (A); NIH3T3 (B); PC12 (C) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.