Application
Sample (30 ug of whole cell lysate) A: Jurkat 7.5% SDS PAGE diluted at 1:1000Application
BACE2 antibody [C1C3] detects BACE2 protein at cytosol on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. BACE2 antibody [C1C3] dilution: 1:500.Application
Immunofluorescence analysis of methanol-fixed A431, using BACE2 antibody at 1:500 dilution.Application
BACE2 antibody [C1C3] detects BACE2 protein at cytoplasm in Rat brain by immunohistochemical analysis. Sample: Paraffin-embedded Rat brain. BACE2 antibody [C1C3] diluted at 1:500.Application
BACE2 antibody [C1C3] detects BACE2 protein at cytosol on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. BACE2 antibody [C1C3] dilution: 1:500.| Product Name | BACE2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to BACE2 (beta-site APP-cleaving enzyme 2)Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human BACE2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
|
| Species Reactivity | HumanRat |
| Predicted Reactivity | Mouse, BovineMouse (88%), Bovine (90%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | AEPLC antibody ALP56 antibody ASP1 antibody ASP21 antibody BAE2 antibody CEAP1 antibody DRAP antibody BACE2 antibody Down syndrome region aspartic protease antibody beta-site amyloid precursor protein cleaving enzyme 2 antibody beta secretase 2 a |
|---|---|
| Molecular Weight(MW) | 56 kDa (note) (2) |
| Cellular Localization | Membrane |
Application
Sample (30 ug of whole cell lysate) A: Jurkat 7.5% SDS PAGE diluted at 1:1000
Application
BACE2 antibody [C1C3] detects BACE2 protein at cytosol on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. BACE2 antibody [C1C3] dilution: 1:500.
Application
Immunofluorescence analysis of methanol-fixed A431, using BACE2 antibody at 1:500 dilution.
Application
BACE2 antibody [C1C3] detects BACE2 protein at cytoplasm in Rat brain by immunohistochemical analysis. Sample: Paraffin-embedded Rat brain. BACE2 antibody [C1C3] diluted at 1:500.
Application
BACE2 antibody [C1C3] detects BACE2 protein at cytosol on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. BACE2 antibody [C1C3] dilution: 1:500.| Positive Control | 293T , A431 , Jurkat , Raji |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
