| Product Name | BAFF receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to BAFF ReceptorMembers in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFFR and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFFR/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF-kappaB and c-jun N terminal kinase. |
| Immunogen | Synthetic peptide (Human). The peptide sequence is identical between human and mouse origin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a concentration of 2 - 5 μg/ml. Predicted molecular weight: 19 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | 10673 603969 Q9Y275 TNFSF20 delta BAFF BAFF TALL1 TALL-1 ZTNF4 TNFSF13B THANK BAFF receptor BLYS TALL 1 |
|---|---|
| Target | BAFF receptor |
| Positive Control | Human, Mouse or Rat spleen tissue lysate. |
|---|---|
| Application Notes | WB: Use at a concentration of 2 - 5 μg/ml. Predicted molecular weight: 19 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Sodium Azide; Constituents: PBS |
