Rabbit Polyclonal antibody to BANF1The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Jan 2009]
Immunogen
BANF1 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human BANF1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAICC/IFWB
WB: 0.5 - 1 ug/ml. IF: 20 ug/ml:
Species Reactivity
Human
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
barrier to autointegration factor 1 NGPS D14S1460 BCRP1 BAF
Target
BANF1
Application
Application
Immunofluorescence of BANF1 in human kidney tissue with BANF1 antibody at 20 μg/mL.
Application
Western blot analysis of BANF1 in human kidney tissue lysate with BANF1 antibody at (A) 0.5 and (B) 1 μg/mL.
Application Notes
WB: 0.5 - 1 ug/ml. IF: 20 ug/ml:
Additional Information
Form
Liquid
Storage Instructions
Stored At 4ºc For Three Months And -20ºc, Stable For Up To One Year. As With All Antibodies Care Should Be Taken To Avoid Repeated Freeze Thaw Cycles. Antibodies Should Not Be Exposed To Prolonged High Temperatures.