Rabbit polyclonal antibody to BCL3 (B-cell CLL/lymphoma 3)This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human BCL3. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, RatMouse (100%), Rat (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
BCL4 antibody D19S37 antibody BCL3 antibody B-cell lymphoma 3-encoded protein antibody proto-oncogene BCL3 antibody B-cell lymphoma 3 protein antibody BCL-3 antibody chronic lymphatic leukemia protein antibody B-cell leukemia/lymphoma 3 antibody B
Target
BCL3
Molecular Weight(MW)
48 kDa (note)
Cellular Localization
Nucleus
Application
Application
Sample (30 ug of whole cell lysate) A: H1299 B: Hela 10% SDS PAGE diluted at 1:1000
Application
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using BCL3 antibody at 1:100 dilution.
Positive Control
A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.