Application
Western blot analysis of extracts from 293 and Hela cells using BCL-XL antibody .| Product Name | Bcl-XL antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Bcl-XLPotent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis. |
| Immunogen | Peptide sequence around aa.60~64 (A-D-S-P-A) derived from human BCL-XL . |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BCL-XL/S BCL2L BCLX BCLXL BCLXS Bcl-X DKFZp781P2092 bcl-xL bcl-xS BCL2L1 apoptosis regulator Bcl-X bcl-2-like protein 1 protein phosphatase 1 regulatory subunit 52 BCL2-like 1 |
|---|---|
| Target | Bcl-XL |
| Molecular Weight(MW) | 30 (note) |
Application
Western blot analysis of extracts from 293 and Hela cells using BCL-XL antibody .| Application Notes | Suggested starting dilutions are as follows. WB: 1:500~1:1000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
