Rabbit polyclonal antibody to BCMAThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Immunogen
Synthetic peptide mapping at the carboxy terminus of human BCMA
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
Western blot analysis (2-6 µg/ml) and Immunohistochemistry (5-20 µg/ml).
Species Reactivity
Human
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
TNFRSF17 , CD269 , BCM
Target
BCMA
Application
Application
WB analysis of K562 (lane 1) and U937 (lane 2) cell lysates using BCMA antibody.
Positive Control
Human spleen tissue
Application Notes
Western blot analysis (2-6 µg/ml) and Immunohistochemistry (5-20 µg/ml).
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.