| Product Name | BDNF antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal [35928.11] to BDNFBrain derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that includes NGF, NT3, and NT4. All neurotrophins have six conserved cysteine residues and share a 55% sequence identity at the amino acid level. BDNF has been shown to enhance the survival and differentiation of several classes of neurons in vitro, including neural crest and placode-derived sensory neurons, dopaminergic neurons in the substantia nigra, basal forebrain cholinergic neurons, hippocampal neurons, and retinal ganglial cells. BDNF is expressed within peripheral ganglia and is not restricted to neuronal target fields, raising the possibility that BDNF has paracrine or even autocrine actions on neurons as well as non-neuronal cells. |
| Immunogen | Recombinant full length human Brain Derived Neurotrophic Factor protein expressed in Sf21 insect cells. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 35928.11 |
| Host Species | Mouse |
| Tested Applications | ELISAWB |
| I-ELISA: Use at a concentration of 0.5-1 μg/ml. WB: Use at a concentration of 1-2 μg/ml. Predicted molecular weight: 26 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Protein A |
| Gene Synonyms | 627 BDNF P23560 113505 MGC34632 |
|---|---|
| Target | BDNF |
| Tissue Specificity | The antibody shows |
| Cellular Localization | Secreted |
| Application Notes | I-ELISA: Use at a concentration of 0.5-1 μg/ml. WB: Use at a concentration of 1-2 μg/ml. Predicted molecular weight: 26 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Constituents: PBS |
