Rabbit Polyclonal antibody to Beta-glucuronidaseThis gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome.[provided by RefSeq, May 2014]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Beta-glucuronidase. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MPS7 , BG , glucuronidase, beta , GUSB
Target
Beta-glucuronidase
Tissue Specificity
Recognizes endogenous levels of Beta-glucuronidase protein.
Application
Application
Western blot analysis of Beta-glucuronidase expression in K562 (A); HeLa (B); HepG2 (C) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.