Application
Immunofluorescence of BFAR in mouse kidney tissue with BFAR antibody at 20 μg/mL.| Product Name | BFAR antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to BFARThe bifunctional apoptosis inhibitor (BFAR) is scaffold protein that integrates signaling components of the cells apoptosis-regulatory machinery. BFAR is a multidomain protein capable of inhibiting apoptosis induced by TNF-family death receptors ('extrinsic pathway') as well as mitochondria-dependent apoptosis ('intrinsic pathway'). Interaction of BFAR with Bcl-2 or Bcl-XL via a SAM domain may contribute to the anti-apoptotic properties of BFAR. In addition, BFAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. BFAR is also thought to be involved in the regulation of neuronal survival. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-P |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BFAR, BAR, Bifunctional apoptosis regulator, RNF47 |
|---|---|
| Target | BFAR |
| Tissue Specificity | This antibody is specific for BFAR |
Application
Immunofluorescence of BFAR in mouse kidney tissue with BFAR antibody at 20 μg/mL.| Positive Control | Blocking Peptide: Cat.No. GTX85010-PEP - BFAR Peptide Lysates: Cat. No. GTX27920 - Human Kidney Tissue Lysate |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Antibody is supplied in PBS containing 0.02% sodium azide |
