Rabbit Polyclonal antibody to BidThis gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]
Immunogen
Recombinant protein of human BID
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:200
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
BH3 interacting domain death agonist , FP497 , BID
Target
Bid
Molecular Weight(MW)
22 kDa (note)
Application
Application
Western blot analysis of extracts of HL60 cell lines, using BID antibody.