Rabbit polyclonal antibody to BmfThe protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Immunogen
Peptide sequence EPSQCVEELEDDV corresponding to amino acids 2-14 of human Bmf.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
Western Blotting: Max Dilution 2 ug/ml Optimal dilution / concentration should be determined by the end user.
Species Reactivity
Human
Predicted Reactivity
Mouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Bcl2 modifying factor , BMF
Target
Bmf
Tissue Specificity
This antibody recognizes Bcl-2 modifying factor (Bmf).
Application
Application
WB analysis of (1)HepG2 and (2)293 cell lysate using Bmf antibody.
Application Notes
Western Blotting: Max Dilution 2 ug/ml Optimal dilution / concentration should be determined by the end user.
Additional Information
Form
Liquid
Storage Instructions
Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.