| Product Name | BMP-2 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to BMP-2BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis. It is also expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary and small intestine. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blotting (0.5-2 µg/ml). It detects the 14 kDa monomer, 28 kDa dimer, as well as the 58 kDa tetramer of human BMP-2. Recombinant human BMP-2 can be used as a positive control. Reactivity to other species has not been tested. | |
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | bone morphogenetic protein 2, BMP-2A, BMP2A, BMP2, BMP-2, BMP 2A, bone morphogenetic protein2, BMP 2 |
|---|---|
| Target | BMP-2 |
| Tissue Specificity | This antibody is specific for BMP-2. |
| Application Notes | Western blotting (0.5-2 µg/ml). It detects the 14 kDa monomer, 28 kDa dimer, as well as the 58 kDa tetramer of human BMP-2. Recombinant human BMP-2 can be used as a positive control. Reactivity to other species has not been tested. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | The antibody solution should be gently mixed before use. Stored at -20 °C for future use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
