Rabbit polyclonal antibody to BMP-4BMPs (bone morphogenetic proteins) belong to the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF-beta superfamily are disulfide-linked dimmers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Species Reactivity
Human
Concentration
0.2mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
BMP4, BMP2B1, bone morphogenetic protein 4, BMP2B, BMP-4, BMP 4, bone morphogenetic protein4
Target
BMP-4
Tissue Specificity
This antibody is specific for BMP-4.
Application
Application
Western blot analysi s of BMP-4 using recombinant human BMP-4
Application Notes
Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually.
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.