Rabbit polyclonal antibody to NIP3 (BCL2/adenovirus E1B 19kDa interacting protein 3)This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. This gene contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein encoded by this gene is known to induce apoptosis, even in the presence of BCL2. [provided by RefSeq]
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BNIP3. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, BovineMouse (100%), Rat (100%), Bovine (100%)
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
NIP3 antibody BNIP3 antibody BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 antibody BCL2/adenovirus E1B 19kDa interacting protein 3 antibody
Target
NIP3
Molecular Weight(MW)
22 kDa (note)
Cellular Localization
Mitochondrion membrane; Single-pass membrane protein , Mitochondrion membrane
Application
Application
Sample (30 ug of whole cell lysate) A: 293T 12% SDS PAGE diluted at 1:500
Positive Control
293T
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.