| Product Name | Bombesin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Bombesin (Gastrin-Releasing Peptide)Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. It has two known homologues in mammals called neuromedin B and gastrin releasing peptide. It works on the gastrointestinal tract neuroendocrine hormone and it stimulates gastrin release from G cells. It activates three different G-protein coupled receptors known as BBR1 2 & 3. It also activates these receptors in the brain. Together with cholecystokinin it is the second major source of negative feedback signals that stop eating behaviour. |
| Immunogen | Synthetic human gastrin releasing peptide (amino acid 14-27) coupled to BSA. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC-FIHC-P |
| Immunohistochemistry 1:50-1:75. This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 to 1:75 with AutoProbe III (GTX28620). It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | 2922 GRP-10 proGRP Bombesin BN preproGRP GRP10 P07492 GRP 137260 GRP 10 |
|---|---|
| Target | Bombesin |
| Tissue Specificity | This antibody is specific to human gastrin-releasing peptide and related peptides (Bombesin). |
| Positive Control | Stomach, Small Intestine |
|---|---|
| Application Notes | Immunohistochemistry 1:50-1:75. This antibody can be used on formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. The antibody may be used at a dilution of 1:50 to 1:75 with AutoProbe III (GTX28620). It is recommended that this product be used on frozen tissue sections or specimens. The optimal conditions should be determined by the individual laboratory.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution, aliquot and store at 4°C. Do not freeze. |
| Storage Buffer | The resulting antiserum is adjusted to standard titer with 0.02M Sodium Phosphate, 0.1M Sodium Chloride, pH 7.3 and 0.05% Sodium Azide. |
