| Product Name | BRAF35 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | BRAF35 Polyclonal antibodyMutations of the human BRCA2 gene confer susceptibility to breast cancer. A structural DNA binding component has been identified and is designated as BRCA2-Associated Factor 35 (BRAF35). There is a close association of the BRAF35/BRCA2 complex with condensed chromatin coincident with histone H3 phosphorylation. Experimental evidence suggests a role for the BRCA2/BRAF35 complex in the modulation of cell cycle progression. |
| Immunogen | Residues 31-50 [KQERGEGPRA GEKGSHEEEP] of the human structural DNA-binding protein BRAF35. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blot – Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry. | |
| Species Reactivity | Human,Mouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Unpurified |
| Gene Synonyms | 605535, SMARCE1r, FLJ26127, 10362, HMGX2, HMG20B, pp8857, Q9P0W2, PP7706, SOXL, BRAF35, BRAF25 |
|---|---|
| Target | BRAF35 |
| Tissue Specificity | Reacts with residues 31-50 [KQERGEGPRA GEKGSHEEEP] of the human structural DNA-binding protein BRAF35. Amino acid identity to mouse = 16/20 (80%). |
| Application Notes | Western blot – Use at 1:500 to 1:1,000 dilution. However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
