Application
IHC-P analysis of human brain tissue using BRCC36 antibody.Application
WB analysis of MCF-7 cell lysate using BRCC36 antibody at (A)0.5, (B)1 and (C)2 ug/ml.| Product Name | BRCC36 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to BRCC36This gene encodes a subunit of the BRCA1-BRCA2-containing complex (BRCC), which is an E3 ubiquitin ligase. This complex plays a role in the DNA damage response, where it is responsible for the stable accumulation of BRCA1 at DNA break sites. The component encoded by this gene can specifically cleave Lys 63-linked polyubiquitin chains, and it regulates the abundance of these polyubiquitin chains in chromatin. The loss of this gene results in abnormal angiogenesis and is associated with syndromic moyamoya, a cerebrovascular angiopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jun 2011] |
| Immunogen | An 18 amino acid peptide from near the amino terminus of human BRCC36. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P,WB |
| WB: 0.5 - 1 ug/ml | |
| Species Reactivity | Human,Mouse,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | BRCA1/BRCA2-containing complex, subunit 3 , CXorf53 , C6.1A , RP11-143H17.2 , BRCC3 |
|---|---|
| Target | BRCC36 |
Application
IHC-P analysis of human brain tissue using BRCC36 antibody.
Application
WB analysis of MCF-7 cell lysate using BRCC36 antibody at (A)0.5, (B)1 and (C)2 ug/ml.| Application Notes | WB: 0.5 - 1 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4oC or at -20oC if preferred. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. |
| Storage Buffer | Phosphate buffered saline and 0.02% Sodium Azide (NaN3) |
