Application
Immunohistochemistry of SMARCA4 in rat brain tissue with SMARCA4 antibody at 5 ug/mL.Application
Western blot analysis of SMARCA4 in SK-N-SH cell lysate with SMARCA4 antibody at 1 ug/ml.| Product Name | BRG1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to BRG1The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
| Immunogen | SMARCA4 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human SMARCA4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA,ICC/IF,IHC-P,WB |
| WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml | |
| Species Reactivity | Human,Rat |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | SNF2LB , SNF2 , BAF190A , MRD16 , SWI2 , hSNF2b , BAF190 , SNF2L4 , SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 , SMARCA4 , RTPS2 |
|---|---|
| Target | BRG1 |
| Tissue Specificity | SMARCA4 antibody is human and rat reactive. Multiple isoforms of SMARCA4 are known to exist. |
Application
Immunohistochemistry of SMARCA4 in rat brain tissue with SMARCA4 antibody at 5 ug/mL.
Application
Western blot analysis of SMARCA4 in SK-N-SH cell lysate with SMARCA4 antibody at 1 ug/ml.| Application Notes | WB: 1 - 2 ug/ml. IHC-P: 5 ug/mL. IF: 20 ug/ml |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
