Application
Sample (30μg whole cell lysate) A:Hep G2 7.5% SDS PAGE diluted at 1:1000| Product Name | Brk antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to Brk (Brk protein tyrosine kinase 6)The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Brk. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Species Reactivity | Human |
| Predicted Reactivity | BovineBovine (80%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | BRK antibody, FLJ42088 antibody, PTK6 antibody, protein-tyrosine kinase 6 antibody, tyrosine-protein kinase BRK antibody, breast tumor kinase antibody, protein-tyrosine kinase BRK antibody, PTK6 protein tyrosine kinase 6 antibody |
|---|---|
| Target | Brk |
| Molecular Weight(MW) | 52 kDa (note) (2) |
| Cellular Localization | Cytoplasm , Nucleus |
Application
Sample (30μg whole cell lysate) A:Hep G2 7.5% SDS PAGE diluted at 1:1000| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
