Rabbit Polyclonal antibody to BRMS1This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BRMS1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IP,WB
Species Reactivity
Human,Monkey,Bovine
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
breast cancer metastasis suppressor 1
Target
BRMS1
Tissue Specificity
Recognizes endogenous levels of BRMS1 protein.
Application
Application
Western blot analysis of BRMS1 expression in HepG2 (A); HeLa (B); K562 (C) whole cell lysates.
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.