Application
Western blot analysis of BTK (pY223) expression in DLD (A); mouse liver (B); rat liver (C); rat kidney (D) whole cell lysates.| Product Name | BTK (phospho Tyr223) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to BTK (phospho Tyr223)The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BTK (pY223). The exact sequence is proprietary. |
| Modification | p-Tyr223 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000 | |
| Species Reactivity | Human,Mouse,Rat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | ATK , Bruton agammaglobulinemia tyrosine kinase , AGMX1 , BPK , BTK , AT , PSCTK1 , XLA , IMD1 |
|---|---|
| Target | BTK |
| Tissue Specificity | Recognizes endogenous levels of BTK (pY223) protein. |
Application
Western blot analysis of BTK (pY223) expression in DLD (A); mouse liver (B); rat liver (C); rat kidney (D) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
