Application
Immunohistochemical analysis of paraffin-embedded human gastric cancer, using C18orf24 antibody at 1:500 dilution.Application
C18orf24 antibody detects C18orf24 protein at cytoplasm in rat testis by immunohistochemical analysis. Sample: Paraffin-embedded rat testis. C18orf24 antibody diluted at 1:500.Application
C18orf24 antibody detects C18orf24 protein at cytoplasm in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. C18orf24 antibody diluted at 1:500.| Product Name | C18orf24 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to C18orf24 (spindle and kinetochore associated complex subunit 1)Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules. |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human C18orf24. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | Human |
| Predicted Reactivity | Rhesus Monkey, BovineRhesus Monkey (94%), Bovine (87%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | C18orf24 antibody MGC10200 antibody SKA1 antibody spindle and KT (kinetochore) associated 1 antibody spindle and kinetochore-associated protein 1 antibody spindle and kinetochore associated complex subunit 1 antibody |
|---|---|
| Molecular Weight(MW) | 29 kDa (note) |
| Cellular Localization | Spindle , Kinetochore |
Application
Immunohistochemical analysis of paraffin-embedded human gastric cancer, using C18orf24 antibody at 1:500 dilution.
Application
C18orf24 antibody detects C18orf24 protein at cytoplasm in rat testis by immunohistochemical analysis. Sample: Paraffin-embedded rat testis. C18orf24 antibody diluted at 1:500.
Application
C18orf24 antibody detects C18orf24 protein at cytoplasm in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. C18orf24 antibody diluted at 1:500.| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
