Rabbit Polyclonal antibody to C3IP1 (kelch-like 12 (Drosophila))Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.
Immunogen
Recombinant protein encompassing a sequence within the center region of human C3IP1. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Zebrafish, Xenopus laevis, Rhesus MonkeyMouse (99%), Rat (99%), Zebrafish (87%), Xenopus laevis (89%), Rhesus Monkey (100%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
C3IP1 antibody DKIR antibody FLJ27152 antibody KLHL12 antibody kelch-like protein C3IP1 antibody kelch-like protein 12 antibody CUL3-interacting protein 1 antibody kelch-like 12 (Drosophila) antibody
Molecular Weight(MW)
63 kDa (note) (3)
Application
Application
Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 7.5% SDS PAGE diluted at 1:1000
Positive Control
NT2D1 , IMR32 , U87-MG , MCF-7
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.