| Product Name | C4d antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Mouse monoclonal antibody [057-51.5.1.6] to C4dThis gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| Immunogen | Purified human C4d |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 057-51.5.1.6 |
| Host Species | Mouse |
| Tested Applications | ELISAFACSIHC-F |
| FACS:1:200~1:500 IHC-F:1:50~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | C4AD CO4 CPAMD2 C4A6 C4A3 complement component 4A (Rodgers blood group) C4A C4 C4S RG C4A4 C4A2 |
|---|---|
| Target | C4d |
| Tissue Specificity | This antibody recognizes a neoantigen on the secreted protein complement component 4d (C4d). |
| Application Notes | FACS:1:200~1:500 IHC-F:1:50~1:100 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4°C or at -20°C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. |
| Storage Buffer | Borate buffered saline containing 0.1% Sodium Azide (NaN3) |
