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C5 antibody

Catalog Number:OM242524
OM242524
Discount Price
OM242524-100ul
1~2 Week
100ul
OM242524-50ul
50ul
OM242524-20ul
20ul
1~2 Week
Product Profile
Product Name C5 antibody
Antibody Type Primary Antibodies
Product description

Rabbit Polyclonal antibody to C5The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to a susceptibility to liver fibrosis and to rheumatoid arthritis. [provided by RefSeq, Jul 2008]

 
Immunogen Recombinant protein of human C5
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications IHCIHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:100:
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms C5a
CPAMD4
C5b
complement component 5
Target C5
Application

Application

Western blot analysis of extract of various cells, using C5 antibody.

Application

Immunohistochemistry of paraffin-embedded human stomach using C5 antibody at dilution of 1:100 (40x lens).

WB

(c) Panel of related target protein expression in the blank group and the low-, medium-, and high-dose ISO groups.(e) Related target protein expression band diagram.

WB

(f) Related target protein expression scatter plots.

WB

(c) Effect of the free radical scavenger NAC on the expression of related target proteins band diagram.

WB

(c) Effect of P53 inhibitor PFT-α on the expression of related target proteins band diagram.

WB

(c) Effect of shRNA-S100-A9 on the expression of related target proteins band diagram.
Application Notes WB: 1:500 - 1:2000. IHC: 1:50 - 1:100:
Additional Information
Form Liquid
Storage Instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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