Rabbit polyclonal antibody to CA11 (carbonic anhydrase XI)Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human CA11. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
:
CARPX1 antibody CA11 antibody CARP-2 antibody carbonic anhydrase-related protein 2 antibody CARP XI antibody carbonic anhydrase-related protein XI antibody carbonic anhydrase-related protein 11 antibody CA-XI antibody CA-RP II antibody carbonic an
Target
CA11
Molecular Weight(MW)
36 kDa (note) (2)
Cellular Localization
Secreted
Application
Application
Sample (30 ug of whole cell lysate) A: A431 10% SDS PAGE diluted at 1:500
Positive Control
A431
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.