Mouse monoclonal antibody [OV185:1] to CA125Several studies have shown that CA125 is useful tumor marker for ovarian epithelial malignancies. However, CA 125 has also been described in other neoplasms such as seminal vesicle and anaplastic lymphomas.
Immunogen
Partially purified human mucin fraction from a pool of cancer tissues of patients with epithelial ovarian.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
OV185:1
Host Species
Mouse
Tested Applications
IHC-P
For IHC-P: Use at a dilution of 1:25-1:50 for 30 min at RT in an ABC method. Requires high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 prior to immunostaining. Optimal dilutions/concentrations should be determined by the researcher.:
Species Reactivity
Human
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
FLJ14303 606154 94025 MUC16 CA125 Q8WXI7
Target
CA125
Tissue Specificity
Reacts specifically with CA 125 ovarian cancer antigen.
Cellular Localization
Extracellular membrane
Light Chain Type
kappa
Application
Application
IHC-P analysis of human ovarian cancer using CA125 antibody [OV185:1].
Positive Control
Ovarian carcinoma
Application Notes
For IHC-P: Use at a dilution of 1:25-1:50 for 30 min at RT in an ABC method. Requires high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 prior to immunostaining. Optimal dilutions/concentrations should be determined by the researcher.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.