Rabbit monoclonal antibody [EPR7916] to CABP1Calcium binding proteins are an important component of calcium mediated cellular signal transduction. This gene encodes a protein that belongs to a subfamily of calcium binding proteins which share similarity to calmodulin. The protein encoded by this gene regulates the gating of voltage-gated calcium ion channels. This protein inhibits calcium-dependent inactivation and supports calcium-dependent facilitation of ion channels containing voltage-dependent L-type calcium channel subunit alpha-1C. This protein also regulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors, P/Q-type voltage-gated calcium channels, and transient receptor potential channel TRPC5. This gene is predominantly expressed in retina and brain. Alternative splicing results in multiple transcript variants encoding disinct isoforms. [provided by RefSeq, Jul 2012]
Immunogen
A synthetic peptide corresponding to residues in human CABP1.
Key Feature
Clonality
Monoclonal
Isotype
IgG
Clone Number
EPR7916
Host Species
Rabbit
Tested Applications
WB
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouse
Concentration
1mg/ml
Target Information
Gene Synonyms
calcium binding protein 1 CALBRAIN HCALB_BR
Target
CABP1
Application
Application
WB analysis of (1) Y79 and (2) U-87 MG lysates (10 μg per lane) using CABP1 antibody [EPR7916] at a dilution of 1:1,000.
Application Notes
WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.