Application
Immunocytochemistry of CaBP7 in HeLa cells with CaBP7 antibody at 4 ug/ml.Application
Western blot analysis of CaBP7 in Hela cell lysate with CaBP7 antibody at (A) 1 and (B) 2 ug/ml.| Product Name | CaBP7 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to CaBP7Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP7 (Calcium-binding protein 7), contains two EF-hand domains for calcium binding and shares 70% homology with CaBP8 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFWB |
| ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Calneuron II Calciumbinding protein7 Calcium-binding protein 7 Calneuron2 Calneuron-2 Calciumbinding protein 7 CALN2 CaBP7 Calneuron 2 Calcium binding protein 7 |
|---|---|
| Target | CaBP7 |
| Tissue Specificity | This antibody is specific for CaBP7 |
Application
Immunocytochemistry of CaBP7 in HeLa cells with CaBP7 antibody at 4 ug/ml.
Application
Western blot analysis of CaBP7 in Hela cell lysate with CaBP7 antibody at (A) 1 and (B) 2 ug/ml.| Positive Control | Blocking Peptide: Cat.No. GTX85169-PEP - CaBP7 Peptide Lysates: Cat. No. GTX27898 - HeLa Cell Lysate |
|---|---|
| Application Notes | ICC/IF:1:200~1:500 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | PBS containing 0.02% sodium azide |
