Application
Western blot analysis of Calcium Sensing Receptor (pT888) expression in MCF7 (A); MDCK (B); U2OS (C); SP2/0 (D); PC12 (E); rat brain (F) whole cell lysates.| Product Name | Calcium Sensing Receptor (phospho Thr888) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Calcium Sensing Receptor (phospho Thr888)The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Calcium Sensing Receptor. The exact sequence is proprietary. |
| Modification | p-Thr888 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseDogRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FIH HYPOC1 GPRC2A HHC1 NSHPT CASR EIG8 PCAR1 FHH HHC calcium-sensing receptor CAR |
|---|---|
| Target | Calcium Sensing Receptor |
| Tissue Specificity | Recognizes endogenous levels of Calcium Sensing Receptor (pT888) protein. |
Application
Western blot analysis of Calcium Sensing Receptor (pT888) expression in MCF7 (A); MDCK (B); U2OS (C); SP2/0 (D); PC12 (E); rat brain (F) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
