Application
Immunofluorescence of CASR in human kidney tissue with CASR antibody at 20 ug/mL.Application
Western blot analysis of CASR in EL4 cell lysate with CASR antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.Application
Immunohistochemistry of CASR in human kidney tissue with CASR antibody at 5 ug/mL.| Product Name | Calcium Sensing Receptor antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Calcium Sensing ReceptorThe protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. [provided by RefSeq, Jul 2008] |
| Immunogen | CASR antibody was raised against a 15 amino acid peptide near the amino terminus of human CASR. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAICC/IFIHC-PWB |
| IF: 20 ug/mL: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | HYPOC1 CASR GPRC2A calcium-sensing receptor FHH HHC FIH NSHPT HHC1 PCAR1 CAR EIG8 |
|---|---|
| Target | Calcium Sensing Receptor |
| Tissue Specificity | CASR antibody is human and mouse reactive. At least two isoforms of CASR are known to exist. |
Application
Immunofluorescence of CASR in human kidney tissue with CASR antibody at 20 ug/mL.
Application
Western blot analysis of CASR in EL4 cell lysate with CASR antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Application
Immunohistochemistry of CASR in human kidney tissue with CASR antibody at 5 ug/mL.| Application Notes | IF: 20 ug/mL: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Be stored at 4oC for three months and -20oC, stable for up to one year. |
| Storage Buffer | PBS containing 0.02% sodium azide. |
